导读:医学界对肥胖与哮喘关系的讨论由来已久，美国研究人员近日在《美国呼吸系统和重症护理医学杂志》上报告说，患有哮喘的儿童长大后更有可能出现肥胖问题
Children with asthma may be at higher obesity risk later in childhood or in adolescence, according to new research published online this week.
据网上新发布的研究报告称，患有哮喘的儿童在童年或者青少年时期更容易出现肥胖问题。
Researchers from the University of Southern California found that young children with asthma were 51 percent more likely to become obese over the next 10 years than children who did not have asthma.
美国南加州大学的研究人员发现，与没有哮喘病史的儿童相比，那些早期患有哮喘的儿童十年后发生肥胖的概率会高出５１％。
However, the good news is that the use of asthma rescue medications reduced the risk of becoming obese by 43 percent.
但好消息是，缓解哮喘症状的药物能将导致肥胖的风险降低43%。
"Asthma and obesity often occur together in children, but it is unclear whether children with asthma are at higher risk for onset of obesity or whether obese children develop asthma, or both," said Zhanghua Chen, a postdoctoral research associate of preventive medicine at the University of Southern California.
南加州大学预防医学博士后研究员陈章华告诉记者：“哮喘和肥胖症状几乎都会在儿童身上出现，不过究竟是哮喘引起的肥胖还是肥胖的儿童更易患哮喘，或者两种情况同时发生，目前还有待研究”
"Our findings add to the literature that early-life asthma history may lead to increased risk of childhood obesity," Chen said.
陈说“我们的发现更倾向于早期的哮喘易导致儿童的肥胖问题。”
Chen and her colleagues looked at 2,171 kindergarteners and first graders who were not obese at the time they were enrolled for the study. At enrollment, 13.5 percent of the children had asthma. During a follow-up of up to 10 years, 15.8 percent of all these children developed obesity.
陈和他的同事们对2,171名幼儿园和小学一年级的孩子进行了健康数据的分析，刚参加研究时这些儿童是没有肥胖问题的，但其中１３．５％的儿童当时患有哮喘。研究人员对这些儿童进行了长达１０年的跟踪随访，研究结束时约15.8%的儿童肥胖。
Researchers confirmed study results in a different group of children, who were recruited in the fourth grade and followed until high school graduation.
从小学四年级观察到高中毕业，研究人员在不同组儿童身上都证实了自己的研究结果。
They found several risk factors for obesity are more prevalent among children with asthma, including reduced physical activity and potential adverse effects from asthma medications.
他们发现引起肥胖的多种风险因素在患有哮喘的儿童身上普遍存在，包括身体活动的减少和服用治疗哮喘药物引起的副作用。
The results also showed that the use of rescue asthma medications appeared to reduce the risk of developing obesity.
研究结果也表明治疗哮喘的药物能降低肥胖的风险。
Overall, the study reinforced the importance of early diagnosis and treatment of asthma, which "may avoid the vicious cycle of asthma increasing the development of obesity with obesity subsequently causing increased asthma symptoms and morbidity leading to further weight gain," they wrote.
总的来说，这项研究的意义在于突出了临床早期诊断和控制儿童哮喘症状的重要性。研究员们表示“这避免了由哮喘引起的恶性循环，预防和控制儿童哮喘对预防今后的肥胖以及肥胖带来的其他慢性病危害具有重要意义。”
The findings were published in the American Journal of Respiratory and Critical Care Medicine
这项研究发现已在美国呼吸和重症监护医学杂志上刊登出版。
