Sure Certainly

No one can be sure how 2009 flu will evolve, but it's certainly not going away.

没有人能够确定2009年的流感将如何演变，但可以肯定的是，其并未走远。

And to a certain extent I am sure this is true - certainly more true than, say, designing another clothing collection, the last century's big solution to a designer's cash flow problems.

从某种程度上讲，我相信这是事实——当然与设计另一个服装系列不同，而设计一个服装系列是上世纪解决设计师现金流问题的最重要方法。

That is, of course it takes many, many years for a woman to cultivate a smile that one suspects is there, but one can't be sure of, and which certainly disappears when scrutinised head on.

那就是，当然，蒙娜丽莎这部作品要达到我们怀疑有“笑”的效果（但没人敢确定是不是真的是笑）要很多很多年，，当近距离直视这部作品的时候又看不出她的笑容。